Question organize clean roms fullset

If I have the DAT file of a console or MAME, is it possible to create my own custom DAT for 1 ROM of each game with the best dump for each region (1 world ROM, 1 USA ROM, 1 Japan ROM, 1 Europe ROM), in the case of MAME, all the official games released up to 2001 and exclude the rest, including all hacks, proto, bad, and other useless ones? Should I keep only the hacks of the versions of Street Fighter 2 and not exclude KOF from 2001 to 2005 (1 ROM for each region)?

Please help me make this...

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